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omentin 1  (MedChemExpress)
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Omentin 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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omentin  (Shanghai Korain Biotech Co Ltd)
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Shanghai Korain Biotech Co Ltd omentin
Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Omentin, supplied by Shanghai Korain Biotech Co Ltd, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human itln1  (Elabscience Biotechnology)
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Human Itln1, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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accessed on 5 december 2025  (Elabscience Biotechnology)
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Accessed On 5 December 2025, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human elisa kit  (BioVendor Instruments)
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Human Elisa Kit, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human omentin elisa kit  (Sunlong Biotech Co Ltd)
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Human Omentin Elisa Kit, supplied by Sunlong Biotech Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human omentin 1 assay kit  (BioVendor Instruments)
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Human Omentin 1 Assay Kit, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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omentin 1  (R&D Systems)
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R&D Systems omentin 1
Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 <t>(300ng/joint/mouse)</t> into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001
Omentin 1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 (300ng/joint/mouse) into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001

Journal: Arthritis Research & Therapy

Article Title: Omentin-1 reduced synovial M1 macrophages through SIRT6 signaling pathway and alleviated knee osteoarthritis response in mice

doi: 10.1186/s13075-025-03680-y

Figure Lengend Snippet: Omentin-1 alleviated pain in ACLT induced SIRT6 −/− OA mice. A Timeline of animal experiments. We performed ACLT surgery to construct wild-type and SIRT6 −/− osteoarthritis (OA) mouse model, and injected 50µL Omentin-1 (300ng/joint/mouse) into the joint cavity of OA mice once a week for 5 consecutive weeks. Behavioral assessment was also performed through pain detection (PWTL) and gait analysis. Knee joint tissue was collected from mice at week 6, with a portion fixed in 4% paraformaldehyde for pathological staining and the remaining portion stored at −80℃ for Western blot analysis. The experimental groups were divided into three groups: Sham group, ACLT group, and Omentin-1 group, with 8 mice in each group. B Pain in OA mice was assessed before surgery and at 1, 2, 3, 4, 5, and 6 weeks after ACLT surgery. (C-E) At the 6th week after surgery, we conducted gait analysis and recorded the swing time, stride length, and paw area of the right hind limb. * p < 0.05, ** p < 0.01, *** p < 0.001

Article Snippet: 24 h after ACLT surgery, two types of mice were injected with Omentin-1 (300ng/50μL, HY-P701099, MedChemExpress) [ ] twice a week into the joint cavity for six consecutive weeks.

Techniques: Construct, Injection, Staining, Western Blot